Unusual thyroid function test (TFT) is defined as TFT result that is incompatible with the normal
physiological relationship between thyroid hormone and TSH/TRH from anterior pituitary and
hypothalamus. It can also be defined by discordant between hormonal and clinical status of patient for example persistently high FT4 but yet the patient is otherwise well with no clinical signs of thyrotoxicosis. Unusual TFT is categorized into 4 broad categories such as normal FT4 with high TSH, normal FT4 with suppression of TSH, high FT4 with high TSH and low FT4 with low TSH. In this lecture l will be sharing some of the cases to illustrate unusual TFT.
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